Published Date: May 25 2023
Recombinant human epidermal growth factor is a small peptide composed of 53 amino acid residues and is a member of the EGF family. It is a multifunctional growth factor that promotes proliferation of various types of cells both in vivo and in vitro. EGF binds to specific receptors on responsive cells, promotes receptor dimerization, and phosphorylates cytoplasmic sites. The activated receptor can bind to at least five proteins with different signal sequences, regulating protein synthesis at the translation level. In addition, EGF can increase the activity of DNA topoisomerases in cells and stimulate the expression of some genes related to proliferation, such as myc and fos.
Pharmacological effects of recombinant human epidermal growth factor
Recombinant human epidermal growth factor such as recombinant human egf promotes the synthesis of DNA, RNA, and hydroxyproline in the process of tissue repair in skin wounds. It induces differentiation of mature epidermal cells into epidermal stem cells and accelerates the generation of granulation tissue and proliferation of epithelial cells in wounds, thus shortening the healing time and improving the quality of wound repair.
Thoroughness: directly reaches the cell nucleus, repairs genes, and promotes cell division, reproduction, and regeneration. It fundamentally treats diseases, elevates body functions, prolongs life, and beautifies appearance.
Fast: it is the highest achievement of genetic engineering and nanotechnology, smaller than cells by 200 times, and can reach the inside of cells within 90 seconds.
Comprehensive: it is inherent in the human body, accompanying life from beginning to end, controlling the whole body, and affecting the entire life process. It is a necessary substance for life activities, the general commander of life activities, directly commanding and regulating the eight major systems of the human body, and activating the cells of the eight major systems to achieve optimal metabolic levels, enabling organs to achieve the best operation, and improving the quality of life.
Safety: recombinant human epidermal growth factor is extracted from natural substances (laboratory fungi, deer antler extract, underwater plant extract, ginsenoside), which is identical to what the human body secretes, and has no toxic side effects or dependence on the human body.
Indications for recombinant human epidermal growth factor:
The recombinant human epidermal growth factor is used for the treatment of burn, scald, and thermal burn wounds (including shallow second-degree and deep second-degree wounds), residual small wounds, and donor skin area wounds, among others.
Recombinant human epidermal growth factor is suitable for the treatment of various types of chronic ulcer wounds (including diabetic, vascular, and radiation ulcers), among others.
Recombinant human epidermal growth factor is suitable for the treatment of various types of fresh and difficult-to-heal skin wounds.
Recombinant human epidermal growth factor is suitable for ordinary wounds, foot gangrene, keratitis, tympanic membrane perforation, bedsores, oral ulcers, freckles, laser surgery protection, and more.